Comparative Molecular Study of Left and Right Colorectal Carcinoma epub
Comparative Molecular Study of Left and Right Colorectal Carcinoma epub

Comparative Molecular Study of Left and Right Colorectal Carcinoma.cFakhraddin Naghibalhossaini
Comparative Molecular Study of Left and Right Colorectal Carcinoma
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Author: Fakhraddin Naghibalhossaini
Number of Pages: 364 pages
Published Date: 12 Apr 2012
Publisher: LAP Lambert Academic Publishing
Publication Country: Germany
Language: English
Format: PDF
ISBN: 9783848428809
File size: 31 Mb
Download Link: Comparative Molecular Study of Left and Right Colorectal Carcinoma
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Epigenetic is one the most important and distinct molecular pathway in colorectal cancer.The epigenetic pathway affect the level of expression of multiple cancer candidate genes essential for cell cycle control, DNA repair, and many others actions within the colon mucosa. Therefore, besides mutations, epigenetic changes including the promoters' methylation of a set of cancer candidate genes (CAN genes) are associated with the CRC progression. Transcriptional silencing by the hypermethylation of CpG islands is an early event in tumor progression and is considered as a methylator phenotype.

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